Job Details

This range is provided by Motion Recruitment. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$50.00/hr - $52.00/hr

Team Lead, Enterprise Talent Services at Motion Recruitment

Our client, a well-known pharmaceutical manufacturer, is urgently looking to hire a Scientist ON SITE in San Diego, CA!

** This is a 12+ month contract to hire on W2 offering a full benefits package **

Required Skills & Experience

• Must have PhD
• 1-2+ years of experience
• Experience with Oligonucleotide analytics
• siRNA experience a MUST
• LCMS experience

Job Responsibilities

• Operating LC-MS systems to perform in-process and final QC of various scales of highly modified oligonucleotides, including siRNA and ASO, to support both discovery portfolio and pre-portfolio projects
• Optimize methods and improve analytical capabilities for novel Oligonucleotide synthesis
• Analyze and optimize methods in a project-specific way (i.e. GalNAc vs Cholesterol vs C16) by denaturing and non-denaturing HPLC methods. In addition, phosphoramidites or lipids by HPLC and LCMS.
• Establish and automate high throughput analytical capabilities and coordinate those efforts with higher synthesis throughput.
• Analyze oligonucleotides by HPLC-SEC, RP-IP and Ion-Exchange Chromatography.
• Continue optimizing siRNAs using best-in-class analytical chemistry methodologies such as different column matrixes for optimal siRNA characterization
• Support integrity confirmation requests (such as concentration) by assay development and biology teams
• Conduct QC for lipid nanoparticle (LNP) formulations of mRNA
• Ensure the supply of laboratory consumables and reagents are in stock as needed
• Maintain a high level of productivity in the laboratory setting.
• Present data and reports on project status at individual, group, and departmental meetings

Seniority level

Associate

Employment type

Contract

Job function

Science and Analyst

Industries

Pharmaceutical Manufacturing and Retail Pharmacies